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Key Features:

BPC-157: A Peptide with Healing Potentials Beyond Gastroprotection

BPC-157 (also known as PL 14736) is a pentadecapeptide. It has the amino acid sequence Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val. This peptide has a molecular formula of C₆₂H₉₈N₁₆O₂₂. The PUBCHEM ID is CID 9941957.

The peptide is banned by the World Anti-Doping Agency in 2022 under the S0 category of non-exempt substances.

There are some tentative pre-clinical studies on animals and in vitro suggesting possible benefit in wound healing and bowel disorders although all of these studies come from a single research group.

BPC-157, scientifically known as Stable Gastric Pentadecapeptide BPC 157 ARG (L-Arginine Salt), is a promising peptide renowned for its healing and protective effects. Numerous animal studies and clinical trials have highlighted its potential therapeutic applications.

At its core, Stable BPC-157 exhibits remarkable gastroprotective properties, offering relief in cases of stomach ulcers, intestinal damage, fistulas, and various inflammatory disorders. Its unique ability to support gastrointestinal health extends beyond the stomach and intestinal tract, demonstrating positive effects in diverse areas of the body.

Unrivaled Stability: A Shield Against Degradation

One of the hallmark features that distinguish STABLE BPC-157 from its acetate salt counterpart is its remarkable stability. In gastrointestinal environments, where acidic conditions prevail, stability is a critical factor for a peptide’s effectiveness. After 5 hours in gastric juice equivalent to a pH of 3.0, STABLE BPC-157 exhibits a degradation rate of merely 5%, a stark contrast to the acetate salt version (Bpc-157 lyophilized powder in vials), which succumbs to over 99% destruction. [ref] This robust stability positions STABLE BPC-157 as the sole peptide capable of retaining its integrity within the harsh gastric environment.

As previously shown (for review, see [1,2,3,4,5,6]), all of the studies to date that have tested the stable gastric pentadecapeptide BPC 157 peptide—native to and stable in human gastric juice, even for periods of time longer than 24 hours! [1–13 ]—as a treatment have demonstrated extremely positive healing effects for various injury types in numerous organ systems, particularly for the muscular system.

The Impervious Shield Against Ultraviolet Light

Furthermore, STABLE BPC-157 distinguishes itself by being impervious to Ultraviolet (UV) light, a characteristic not shared by other peptides. When exposed to UV light at a wavelength of 253.7nm over 70 minutes, STABLE BPC-157 remains unharmed and stable throughout. This exceptional resistance to UV light underscores the peptide’s resilience and suggests that it can maintain its efficacy even under conditions that might compromise other peptides. This unique attribute is a testament to the robust nature of STABLE BPC-157, positioning it as a versatile and durable therapeutic agent.

Multifaceted Healing: Beyond Stability

The advantages of STABLE BPC-157 extend far beyond its stability. This peptide demonstrates a wide range of therapeutic benefits, making it a promising candidate for various medical applications.

Wound and Gut Healing: STABLE BPC-157 has shown significant potential in promoting wound healing and gastrointestinal repair. Its ability to accelerate tissue regeneration makes it a valuable asset in addressing injuries and gastrointestinal issues.
Muscle, Tendon, Ligament, and Bone Repair: The peptide has demonstrated efficacy in promoting the repair of musculoskeletal tissues, including muscles, tendons, ligaments, and bones. Studies indicate its positive impact on bone healing, with potential implications for fracture recovery and overall skeletal health. The peptide’s role in promoting bone density and strength contributes to its overall therapeutic appeal. This property makes it particularly relevant for applications in sports medicine and orthopedics.
Cell Growth and Angiogenesis: STABLE BPC-157 has been linked to the stimulation of cell growth and angiogenesis, the formation of new blood vessels. This suggests its potential in supporting tissue regeneration and overall physiological balance.
Drug Side Effects, Ulcers, and Heart Attacks: The peptide exhibits protective effects against drug-induced side effects, ulcers, and heart attacks. Its ability to mitigate the adverse effects of certain medications and contribute to cardiovascular health adds to its therapeutic versatility.
Anti-Inflammatory and Antioxidant: STABLE BPC-157 has demonstrated anti-inflammatory and antioxidant properties. This dual action positions it as a potential intervention for conditions characterized by inflammation and oxidative stress.
Brain-Gut Axis Benefits and Antidepressant: The peptide’s influence on the brain-gut axis suggests its potential in addressing conditions related to the interconnectedness of the gut and the central nervous system. Additionally, it exhibits antidepressant properties, hinting at its role in mental health. This intriguing aspect opens avenues for exploring BPC-157’s role in supporting cognitive health and addressing certain brain-related conditions.
Eye Healing: STABLE BPC-157 has shown promise in promoting eye healing. Its potential in addressing ocular conditions further expands its applicability in the field of ophthalmology.
Conclusion

STABLE BPC-157 arginine salt peptide stands as a remarkable achievement in the realm of peptide therapeutics, combining exceptional stability with a diverse array of healing properties. Its ability to withstand the challenges posed by gastric conditions and ultraviolet light sets it apart, making it the peptide of choice for researchers and clinicians seeking stability and efficacy across various environments.

Stable BPC-157, with its primary focus on gastroprotection, has emerged as a multifaceted peptide with far-reaching healing potentials. From addressing stomach ulcers and intestinal damage to promoting collagen regeneration in bones and joints, the peptide showcases a diverse range of therapeutic applications. Its influence on organ recovery and potential neuroprotective effects add further layers to its promising profile. As ongoing research continues to unveil the full extent of its therapeutic potential, STABLE BPC-157 holds the promise of revolutionizing treatment approaches in wound healing, musculoskeletal repair, anti-inflammatory interventions, and beyond.

A singular extensively researched and verified variant of BPC-157 exists, identified as the STABLE BPC-157 version presently provided by Xcel Peptides.

Xcel Peptides’ STABLE BPC-157 represents the pinnacle of scientific advancement, presenting a user-friendly tablet format as the most sophisticated “stabilized” iteration of this compound.